Patient-Centered Outcomes Research InstituteCOVID-19 Targeted PFA - Cycle 2 2020
This research funding announcement, with an accelerated timeline, supports innovative, high-impact studies that fit clearly within our core mission of patient-engaged and patient-centered comparative clinical effectiveness research. The objectives of this announcement are to (1) strengthen the understanding of different approaches to mitigate the impact of COVID-19 on individuals, communities, healthcare providers, and healthcare systems; and (2) provide evidence to inform clinical and public health responses, decision making, and planning.
- Is there a Letter of Intent (LOI) requirement for this PFA?
- What are the required application templates?
- How do you partner with PCORnet?
- Can the trial partner be a federal agency?
- Are patients from other countries allowed to participate in the study?
- Can an organization submit more than one application for the COVID-19 PFA?
- Will my application be viewed more favorably if it addresses more than one of the priority research questions?
- Can my proposed study address one of the priority research questions but only for a specific population?
- Is the COVID-19 Targeted PFA a one-time solicitation?
- What does PCORI consider sufficient evidence of efficacy for strategies addressing the impact of COVID-19?
- What if there are no systematic reviews on the research gap my research study will address?
- Will PCORI consider funding a COVID-19 study that includes a usual care group?
- If I have a design that compares the effectiveness of two alternatives, would it be acceptable to include usual care as a third arm?
- What types of study designs are acceptable under the COVID-19 Targeted PFA?
- What is a hybrid design, and why is that called out in the COVID-19 funding announcement?
- Are descriptive studies that examine the impact of COVID-19 on the health system, patients, caregivers, health care providers acceptable under this PFA?
- Are applications that propose to study the effectiveness of psychosocial interventions responsive to the COVID-19 PFA?
- What do you mean by powering the study for subgroups of interest?
- How should applicants address the PCORI Methodology Standards in an application?
- How much stakeholder involvement is acceptable for PCORI requirements under the COVID-19 PFA?
- May I analyze the engagement methods that are used in the study and if so, how much of the award can be applied to those efforts?
- May I contact someone at PCORI about the suitability of my proposed project?
- Can I propose a study utilizing the Healthcare Worker Exposure Response and Outcomes (HERO) registry?
- Is a hybrid design acceptable?
- Is it a requirement for subcontractors to be identified and in place prior to submission of the application? Are detailed budgets for subcontractors required at the time of application submission?