Supplemental Funding for Existing PCORI-funded Comparative Clinical Effectiveness Research to Improve Understanding of Patient-Centered Economic Outcomes

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• What does "awardees are encouraged to think about analysis that explores these factors in some depth, while avoiding aggregating or comparing total costs of care" mean?
• What is meant by "analyses that focus on a cost comparison to determine (or that could be interpreted as determining) a preferred intervention?"
• What are "total cost comparisons, cost-effectiveness analysis (CEA) or related types of economic evaluation?"
• What "social risk factors and/or social determinants of health on costs and other economic burdens incurred by patients, caregivers and other stakeholders" are acceptable?
• What is meant by “perspectives” in "Analysis should synthesize findings of costs and other economic burdens from the perspectives of the different stakeholders for whom such data are proposed to be collected as part of the supplement?"
• I do not have the ability to measure costs incurred by stakeholders besides patients or caregivers. Do I qualify?
• What costs are acceptable besides time away from usual activities, out-of-pocket costs, time spent caregiving, perceived financial toxicity and changes in health care utilization?
• I have the ability to measure caregiver, but not patient, costs. Do I qualify?
• I do not have the ability to measure patient or caregiver costs. Do I qualify?
• What does "rigorous, established methodologies" mean?
• What does "credible data on costs and other economic burdens" mean?
• What does "capability of collecting and analyzing data" mean?
• What does "support patients and other stakeholders in making informed health care decisions that account for such impacts" mean?
• What does "meaningful to and inclusive of patients, caregivers and other stakeholders" mean?
• What are "appropriate and relevant costs and other economic burdens?"
• Where do I direct my questions related to these supplemental funding opportunities?
• Am I able to submit multiple requests to one or both supplemental funding opportunities?
• Will I have an opportunity to revise and resubmit if my request is not funded?
• Do the eligibility criteria for each supplement differ?
• What are the eligibility criteria for each supplement?