I have been invited to submit a full application based on my accepted LOI. Am I allowed to make any changes from the approved LOI to be reflected in my full application?

You are invited to submit an application based on the information provided in the LOI.  Any changes to the following require PCORI’s approval:

• PI (Contact PI and Dual-PI, if applicable)
• Institution
• Study design
• Research question(s)
• Primary outcome measure(s)
• Specific aims
• Comparators

If you need to change any of this information or have any questions, email pfa@pcori.org.