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What is the difference between PCORI’s National Priority Areas for Health, eight topic themes, and the four ongoing key topics identified within the BPS PFA?

The 2023 BPS PFA seeks applications that address four of PCORI’s five National Priorities for Health. To be considered responsive, applications must describe research that compares at least two alternative approaches to achieve one or more of the National Priorities for Health. Applicants will be asked to select a primary National Priority, and, if relevant, a secondary and/or tertiary National Priority in their Letters of Intent, and if invited, in their full application.

In addition, this first cycle of the 2023 Broad Pragmatic Studies PFA is the inaugural issuance of a funding opportunity that addresses PCORI's topic themes.  In Summer 2022, PCORI’s Board of Governors approved a set of eight broad topic themes that will inform PCORI’s funding opportunities over the next several cycles. The topic themes were distilled from public input received from a broad spectrum of stakeholders, including formal public comments made during PCORI’s strategic planning efforts.  Within Letters of Intent and Applications, applicants will be asked to designate the primary, and as applicable, secondary and/or tertiary topic theme(s) with which their proposed research most closely aligns. Applicants may also select “other” if their research does not align with any listed theme.  Additional information about the topic themes and example projects is available on the PCORI website.

In addition to the above topic themes, PCORI also seeks applications related to four ongoing key topics—improving outcomes for people with intellectual and developmental disabilities; preventing maternal morbidity and mortality; COVID-19; and rare disease, the first two representing ongoing priorities named in PCORI’s 2019 authorizing legislation. Applicants will also be asked to select any key topic to which their research best aligns, as applicable.

As mentioned above, submissions are not limited to these topic themes and key topics; however, all applications under the BPS PFA must select at least one of the four PCORI National Priorities for Health.

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