My LOI Was Accepted And I Was Invited To Submit My Application Under Category 1 (Proposed Budget Less Than Or Equal To $5 Million). However, Our Proposed Budget Increased In Preparing Our Application. Can I Submit My Full Application Under Category 2?

PCORI understands that the budget provided during LOI submission is an estimate and that the budget may change by the time of application submission.  

Applicants are permitted to submit their full application to either Category, regardless of what was approved at the LOI stage.  Prior approval from PCORI is not required.