PCORI Help Center

How much can the protocol proposed in my application differ from that initially described in my LOI?

Applicants should not make major changes to their application, including changes to implementation approach, specific aims, institution, or PI without prior approval from the D&I Program. Applicants are invited to apply based on the information provided in the LOI. If you need to change any of this information or have any questions, email pfa@pcori.org.

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