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What types of study designs are acceptable under the COVID-19 Targeted PFA?

Diverse methods, including interventional studies and the use of natural experiments to conduct research on an accelerated timeline are acceptable. In all cases, applicants are expected to justify how their chosen study design is appropriate to answer their research questions.

Applicants are encouraged to complete primary outcomes collection and provide actionable findings in no longer than 12 months. Hybrid designs, which can provide insight into implementation approaches in the context of evidence generation, will also be welcome.

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