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Will PCORI consider applications that address a rare disease population already included in the PCORI research portfolio?

PCORI is particularly interested in funding studies for rare diseases that are not well represented in PCORI’s rare disease research portfolio. However, if the applicant can convincingly make the case that the specific interventions and comparators proposed represent a compelling decisional dilemma and will fill an important patient-centered research gap, PCORI will consider such applications.

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