PCORI Help Center

What types of observation studies PCORI would be interested in for this PFA?

PCORI is interested in observational studies that direct address the two questions within the funding announcement. Investigators should provide a rationale for the selection of the comparators of interest. While we generally expect that these will be prospective studies, it may also appropriate to propose a quasi-experimental design. Investigators should address potential issues of confounding within any observational study design.

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