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PCORI discourages proposals in the following categories, and will deem them nonresponsive:
- Instrument development, such as new surveys, scales, etc.
- Developing, testing, and validating new decision aids and tools, or clinical prognostication tools
- Pilot studies intended to inform larger efforts
- Comparing patient characteristics rather than clinical strategy options
Consistent with PCORI's authorizing law, PCORI does not fund research whose findings will include:
- Coverage recommendations
- Payment or policy recommendations
- Creation of clinical practice guidelines or clinical pathways
- Establishment of efficacy for a new clinical strategy
- Pharmacodynamics
- Study of the natural history of disease
- Basic science or the study of biological mechanisms
Studies of Cost-Effectiveness
PCORI will consider an application nonresponsive if the proposed research:
- Conducts a formal cost-effectiveness analysis of alternative approaches to providing care
- Directly compares the costs of care between two or more alternative approaches to providing
care
Please be sure to review the Submission Instructions for your PFA for further clarification.