What research does PCORI NOT fund?

PCORI discourages proposals in the following categories, and will deem them nonresponsive:

• Instrument development, such as new surveys, scales, etc.
• Developing, testing, and validating new decision aids and tools, or clinical prognostication tools
• Pilot studies intended to inform larger efforts
• Comparing patient characteristics rather than clinical strategy options

Consistent with PCORI's authorizing law, PCORI does not fund research whose findings will include:

• Coverage recommendations
• Payment or policy recommendations
• Creation of clinical practice guidelines or clinical pathways
• Establishment of efficacy for a new clinical strategy
• Pharmacodynamics
• Study of the natural history of disease
• Basic science or the study of biological mechanisms

Studies of Cost-Effectiveness
PCORI will consider an application nonresponsive if the proposed research:

• Conducts a formal cost-effectiveness analysis of alternative approaches to providing care
• Directly compares the costs of care between two or more alternative approaches to providing
  care

Please be sure to review the Application Guidelines for your PFA for further clarification.