Yes. However, PIs are invited to submit an application based on the information provided in the LOI. Any changes to the following require PCORI's written approval prior to submission:
- Principal Investigator
- Institution
- Study design
- Research question(s)
- Specific aims
- Comparators
Please email pfa@pcori.org regarding information you would like to change or if you have any questions. Due to the volume of requests PCORI received, applicants should submit the request early during the application process.