A PI may submit multiple LOIs in a cycle. However, they can only submit one distinct LOI per PFA. If a PI submits an LOI to multiple PFAs, he or she must ensure that the research topics/projects are not similar. LOI submissions that show scientific overlap or appear to be duplicate in nature will be disqualification. If this were to occur, PCORI will contact the PI to determine which PFA he or she would like to apply to.
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