Are PIs eligible to apply to multiple funding announcements during the same cycle?

Yes, a PI may submit multiple LOIs in a cycle. However, the same project may not be submitted to multiple PCORI Funding Announcements (PFAs) in a given cycle. If a PI submits an LOI to multiple PFAs, he or she must ensure that the research topics/projects are not similar. LOI submissions that show scientific overlap or appear to be duplicate in nature will be disqualified. If this were to occur, PCORI will contact the PI to determine which PFA he or she would like to apply to.

In general, a Principal Investigator (PI) can submit only one LOI per PFA. However,
because PCORI’s Broad PFA included funding opportunities across the four distinct PCORI
National Research Priorities, it is permissible for a PI to submit multiple LOIs under different
national research priority areas. The research topics and projects must be distinct and responsive to the
specific respective national research priority areas, as outlined in the PFA. Moreover, an individual listed
as a PI on one LOI may be listed as and serve in another role (e.g., co-PI, co-investigator, or consultant)
on other LOIs within the same PFA during the same cycle. A PI may submit multiple LOIs to different
program PFAs in a cycle, but the PI must ensure that the research topics and projects are not similar. If a
PI submits an LOI to multiple program PFAs, LOIs that exhibit scientific overlap or that appear to be
duplicate submissions will be disqualified. PCORI will contact the PI and provide him or her with an
opportunity to choose which PFA he or she would like to apply to. This applies to single- and dual-PI
submissions.