LOIs will be reviewed by PCORI program staff for responsiveness to this PFA and fit to program goals. Letters will be evaluated based on responses to all items listed in the LOI Template, including whether the proposed topic addresses the priority research question identified in the funding announcement; importance of the specific research question; study design, including having an appropriate, well justified sample size; and prior relevant research experience. The LOI must also comply with requirements in this funding announcement and adherence to the administrative and formatting requirements listed in the Application Guidelines, specifically the three-page limit (excluding references) for the LOI. Prospective applicants who submitted LOIs to this funding announcement will be notified by dates specified in each PFA, about whether they have been selected to submit a full application. PCORI will accept full applications from only the selected LOIs.
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