Can I change information from the LOI stage to the application stage?

Yes. However, you are invited to submit an application based on the information provided in the LOI. Any changes to the following require PCORI's written approval before submission:

• PI
• Institution
• Implementation approach
• Specific aims
• SDM approach

If you need to change any of this information or have any questions, email pfa@pcori.org. Due to the volume of requests PCORI receives, applicants should submit the request early.