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Does my application need to address information related to participant randomization, retention, or attrition?

Yes, please be sure to include a plan for the feasibility of the study design, describing how randomization will occur between different sites and locations. Include in the plan evidence showing that patients would be willing to be randomized to specific locations. The proposal should also address participant retention and projected attrition rates. An appropriate attrition rate should be accounted for in final recruitment numbers and included in the power analysis.

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