PCORI Help Center

Will this funding opportunity consider the comparison of novel pharmacological interventions/interventions that do not yet have established efficacy (are not evidence-based) in certain groups, such as pediatric, adolescent and/or geriatric populations?

If comparators do not have established efficacy in the population of interest, applicants should provide documentation of widespread use for these drugs in the population of interest to demonstrate a high degree of use in clinical practice.

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