Will this funding opportunity accept proposals aiming to develop phone apps, instruments, etc., for the prevention of migraines?

No. Projects aiming to develop new interventions that lack evidence of efficacy or effectiveness, such as instrument development; app development; developing, testing, and validating new decision aids and tools; or clinical prognostication tools will be considered out of scope. The comparison of an evidence-based and/or in widespread use phone app + another evidence-based and/or in widespread use phone app or pharmacological/non-pharmacological intervention may be responsive if applicants can justify the selection of the proposed comparators.