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What does "awardees are encouraged to think about analysis that explores these factors in some depth, while avoiding aggregating or comparing total costs of care" mean?

Awardees are reminded that PCORI will not fund research that compares and contrasts interventions on the basis of comparative costs or cost effectiveness. This means that aggregating or comparing total costs will not be funded. Awardees are encouraged to consider how the domains of cost and other economic burdens that are feasible within their study can be explored to better understand how these costs arise, how they vary and how they affect patients, caregivers and other stakeholders. 

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